From: Hyundeok Song (
Date: Mon Aug 11 2008 - 11:18:54 CDT

Hi all

I have a question abut a membrane in Gramicidin channel.
I studied below site.

Building Gramicidin A

Tutorial used POPE membrane.
palmitoyl-oleoyl-phosphatidylethanolamine (POPE)

Also, I saw many papers used DMPC membrane instead of POPE in Gramicidin. dimyristoyl-phosphatidylcholine(DMPC)

I drawed the chemical structure of DMPC and POPE and searched the difference between DMPC and POPE in Gramicidin. But, I still don't know why some use POPE and others use DMPC in Gramicidin. What is the difference between them in Gramicidin?

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