Yupeng Li

Home Department: Center for Biophysics and Quantitative Biology

Office Address: 3115 Beckman Institute, 405 N Matthews Ave, Urbana, IL 61801

Email Address: yupengl3@illinois.edu

Education

University of Illinois at Urbana-Champaign, Urbana, IL, USA

Ph.D in Center for Biophysics and Quantitative Biology (expected 2026)

Jilin University, Changchun, Jilin, China

B.S. in Tang Aoqing Honors Program in Chemistry (2020)

Research Interests

Protein-lipid interactions (peripheral proteins such as OhyA)
Membrane transporters (MmpL3)
Large protein machinery (Lpt and LetAB)

Selected Publications

^* denotes co-authors.

Radka, C.D., Grace, C.R.,Hasdemir, H.S.^*, Li, Y.^*, Rodriguez, C.C., Rodrigues, P., Oldham, M.L., Qayyum, M.Z., Pitre, A., MacCain, W.J. and Kalathur, R.C. The Carboxy Terminus Causes Interfacial Assembly of Oleate Hydratase on a Membrane Bilayer. Journal of Biological Chemistry. 300(2) (2024).

Y. Li^*, A. Acharya^*, L. Yang, J. Liu, E. Tajkhorshid, H .I. Zgurskaya, M. Jackson and J .C. Gumbart. Insights Into Substrate Transport and Water Permeation in the Mycobacterial Transporter MmpL3. Biophysical Journal. 122(11):2342-2352 (2023).

C. M. Stevens, S. O. Babii, A. N. Pandya, W. Li, Y. Li, J. Mehla, R. Scott, P. Hegde, P. K. Prathipati, A. charya, J. Liu, J. C. Gumbart, J. North, M. Jackson and H. I. Zgurskaya. Proton Transfer Activity of the Reconstituted Mycobacterium Tuberculosis MmpL3 is Modulated by Substrate Mimics and Inhibitors. PNAS. 119(30):e2113963119 (2022).

Y. Li, J. Liu and J. C. Gumbart. Preparing Membrane Proteins for Simulation Using CHARMM-GUI. Structure and Function of Membrane Proteins. 237-251 (2021).