TCBG Seminar

Advances and limitations in force spectroscopy of bio-molecules

Professor Thomas T. Perkins
JILA, National Institute of Standards and Technology and University of Colorado
Unknown Institution
Boulder, CO

Monday, October 18, 2010
11:00 am (CT)
3269 Beckman Institute


Force spectroscopy is an important single-molecule technique to study the energetics and dynamics of biological systems. Both optical traps and atomic force microscopes (AFMs) can measure the dynamics of individual molecules. My talk will focus on two intellectually distinct experiments: (i) advances in precision force spectroscopy of membrane proteins based on an optically stabilized AFM and (ii) limitations in active feedback loops to hold DNA hairpins under constant force.

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