Forsythe, Jay G.; Petrov, Anton S.; Walker, Chelsea A.; Allen, Samuel J.; Pellissier, Jarrod S.; Bush, Matthew F.; Hud, Nicholas V.; Fernandez, Facundo M.
Collision cross section calibrants for negative ion mode traveling wave ion mobility-mass spectrometry
ANALYST, 14:6853-6861, 2015

Unlike traditional drift-tube ion mobility-mass spectrometry, traveling-wave ion mobility-mass spectrometry typically requires calibration in order to generate collision cross section (CCS) values. Although this has received a significant amount of attention for positive-ion mode analysis, little attention has been paid for CCS calibration in negative ion mode. Here, we provide drift-tube CCS values for [M - H](-) ions of two calibrant series, polyalanine and polymalic acid, and evaluate both types of calibrants in terms of the accuracy and precision of the traveling-wave ion mobility CCS values that they produce.

DOI:10.1039/c5an00946d

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