Structural Biology Software Database
Structural Biology Software Database

Application Index Record

Category: Molecular Biology Resources and Databases
CATH (Protein Structure Classification)
Last Update: 11-28-2001

Description:
The CATH database is a hierarchical domain classification of protein structures in the Brookhaven protein databank. All non-protein, model, and "C-alpha only" structures are not classified in CATH. Only crystal structures solved to resolution better than 3.0 angstroms are considered, together with NMR structures. This filtering of the Brookhaven databank is performed using the program SIFT (Michie et al, (1996)). There are four major levels in this hierarchy; Class, Architecture, Topology (fold family) and Homologous superfamily. Each level is described below, together with the methods used for assigning structures to a specific family.

Homepage:
http://www.biochem.ucl.ac.uk/bsm/cath_new/index.html

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