TCB Publications - Abstract

TCB Publications - Abstract

Manel A. Balsera, Willy Wriggers, Yoshitsugu Oono, and Klaus Schulten. Principal component analysis and long time protein dynamics. Journal of Physical Chemistry, 100:2567-2572, 1996.

BALS96 It has been suggested that principal component analysis can identify slow modes in proteins and, thereby, facilitate the study of long time dynamics. However, sampling errors due to finite simulation times preclude the identification of slow modes that can be used for this purpose. This is demonstrated numerically with the aid of G-actin simulations, and analytically with the aid of a model which is exactly recoverable by Principal Component Analysis.

Download Full Text

The manuscripts available on our site are provided for your personal use only and may not be retransmitted or redistributed without written permissions from the paper's publisher and author. You may not upload any of this site's material to any public server, on-line service, network, or bulletin board without prior written permission from the publisher and author. You may not make copies for any commercial purpose. Reproduction or storage of materials retrieved from this web site is subject to the U.S. Copyright Act of 1976, Title 17 U.S.C.

Download full text: Journal, Request a Copy