Tutorial-l Mailing List

From: Hyundeok Song (songhk_at_email.uc.edu)
Date: Mon Aug 11 2008 - 11:18:54 CDT

Hi all

I have a question abut a membrane in Gramicidin channel.
I studied below site.

Building Gramicidin A
http://www.ks.uiuc.edu/Research/namd/tutorial/NCSA2002/hands-on/

Tutorial used POPE membrane.
palmitoyl-oleoyl-phosphatidylethanolamine (POPE)

Also, I saw many papers used DMPC membrane instead of POPE in Gramicidin. dimyristoyl-phosphatidylcholine(DMPC)

I drawed the chemical structure of DMPC and POPE and searched the difference between DMPC and POPE in Gramicidin. But, I still don't know why some use POPE and others use DMPC in Gramicidin. What is the difference between them in Gramicidin?
thanks.

Hyun.
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