VMD-L Mailing List

From: Ashar Malik (asharjm_at_gmail.com)
Date: Mon Jun 11 2018 - 00:22:13 CDT

Have you tried using Modeller.
https://salilab.org/modeller/wiki/Mutate%20model

The script provided in the above example is simple to use. You give it the
protein name (same as file name except the ".pdb" part), the residue
position to mutate, the residue name to mutate to and the chain and that's
it. Line 13 in the script gives more details on the usage of the script.

On Mon, Jun 11, 2018 at 9:51 AM Bose, Ritwika <ritwika.bose_at_richmond.edu>
wrote:

> Hello,
> I am a student at University of Richmond, working with a Virus like
> particle bacteriophage. I was trying to mutate one of the residues on the
> monomer to another, but despite following all the steps, the software
> generates the MUTATED file without any changes to the intended amino acid
> at all. The monomer consists of 3 chains and I wondered if that could be an
> issue. I would appreciate any help on this matter.
> Thank you,
> Ritwika Bose
> 

-- 
Best,
/A