Russel, Daniel; Lasker, Keren; Phillips, Jeremy; Schneidman-Duhovny, Dina; Velazquez-Muriel, Javier A.; Sali, Andrej
The structural dynamics of macromolecular processes
CURRENT OPINION IN CELL BIOLOGY, 21:97-108, FEB 2009

Dynamic processes involving macromolecular complexes are essential to cell function. These processes take place over a wide variety of length scales from nanometers to micrometers, and over time scales from nanoseconds to minutes. As a result, information from a variety of different experimental and computational approaches is required. We review the relevant sources of information and introduce a framework for integrating the data to produce representations of dynamic processes.

DOI:10.1016/j.ceb.2009.01.022

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