Structural Biology Software Database
Structural Biology Software Database

Application Index Record

Category: Molecular Building
EGAD: protein design and mutant stability and affinity prediction
Last Update: 07-17-2006

Description:
EGAD is a free, open-source software package for protein design and prediction of mutation effects on protein folding stabilities and binding affinities to 1kcal/mol. EGAD can also consider multiple structures simultaneously for designing specific binding proteins or locking proteins into specific conformational states. In addition to natural protein residues, EGAD can also consider free-moving ligands with or without rotatable bonds. EGAD can be used with single or multple processors.

Homepage:
http://egad.ucsd.edu/EGAD_manual/index.html

Download Page:
http://egad.ucsd.edu/EGAD_manual/EGAD.tar.gz

Documentation Page:
http://egad.ucsd.edu/EGAD_manual/table_of_contents.html

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