Structural Biology Software Database
Structural Biology Software Database

Application Index Record

Category: DNA, RNA and Protein Stucture Prediction
kPROT
Last Update: 04-06-2001

Description:
kPROT is a WWW service for structure prediction of membrane proteins, specifically designed for transmembrane proteins with multiple alpha-helical spans. It provides a prediction of the angular orientation of the segment. You submit protein sequence(s) of previously identified transmembrane segment. The server predicts the helical orientation of the segment as expected to be when embedded in a helical bundle within the membrane i.e. lipid-exposed vs. protein-buried faces of alpha-helices The Helical orientation predictions are done with the "knowledge-based Propensities for Residue Orientation in Transmembrane segments" (kPROT) energy-like scale.

Homepage:
http://bioinformatics.weizmann.ac.il/kPROT/

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