Bioinformatics
The research on bioinformatics in this group is focused upon different levels of description:
- On sequence
level both standard methods as well as customized algorithms
are used to analyze organization and expression of genomes of various
origins.
- By utilizing the knowledge on biopolymer structures of the group new methods are developed to characterize novel genes.
- A graph-topological as well as dynamical approach towards a functional description of genes and gene families interacting within regulatory or metabolic networks is made.
- By utilizing the knowledge on biopolymer structures of the group new methods are developed to characterize novel genes.
All three levels interact with each other yielding a comprehensive picture of todays accessible genomes. Special care is taken to frame this research in an evolutionary context. Evolution and self-organization of former individual subsystems to larger systems is a major research task.
Bioinformatics Links can be found here
Publications
- [1] C. V. Forst, and K. Schulten. "Evolution of Metabolisms: A new Method for the Comparison
- of Metabolic Pathways",
Proceedings of the Third Annual International Conference on
Computational Molecular Biology, Lyon, France.
Sorin Istrail, Pavel Pevzner, Michael Waterman, eds.,
pp. 174-180, ACM Press, New York, 1999.