FEP/λ-REMD Simulation error

From: Alao, John-Paul (alaooj_at_miamioh.edu)
Date: Mon Nov 09 2020 - 11:01:26 CST

Dear mailing list,

I generated the configuration files to run absolute protein-ligand binding
free energy using Charmm-GUI. However, this part of the code crashes.

# FEP/λ-REMD Simulation, Runing 4 ns (200 ps x 20)
cnt=0
cntmax=20

while [ ${cnt} -le ${cntmax} ]
do
    if [ ${cnt} -eq 0 ]
    then
        charmrun /software/NAMD/NAMD_2.13_Linux-x86_64-multicore/namd2 +p24
+replicas 24 fep_${system}.conf --source FEP_remd_softcore.namd +stdout
output_${system}/%d/job${cnt}.%d.log
    else
        charmrun /software/NAMD/NAMD_2.13_Linux-x86_64-multicore/namd2 +p24
+replicas 24 restart_${cnt}.conf --source FEP_remd_softcore.namd +stdout
output_${system}/%d/job${cnt}.%d.log
    fi
    cnt=$[$cnt+1]
done

*The error message is:*

Running command: /software/NAMD/NAMD_2.13_Linux-x86_64-multicore/namd2 +p24
+replicas 24 fep_solv.conf --source FEP_remd_softcore.namd +stdout
output_solv/%d/job0.%d.log

Charm++: standalone mode (not using charmrun)
Charm++> Running in Multicore mode: 24 threads
./fep.sh: line 40: 106230 Segmentation fault (core dumped) charmrun
/software/NAMD/NAMD_2.13_Linux-x86_64-multicore/namd2 +p24 +replicas 24
fep_${system}.conf --source FEP_remd_softcore.namd +stdout
output_${system}/%d/job${cnt}.%d.log
Running command: /software/NAMD/NAMD_2.13_Linux-x86_64-multicore/namd2 +p24
+replicas 24 restart_1.conf --source FEP_remd_softcore.namd +stdout
output_solv/%d/job1.%d.log

Charm++: standalone mode (not using charmrun)
Charm++> Running in Multicore mode: 24 threads
./fep.sh: line 40: 106232 Segmentation fault (core dumped) charmrun
/software/NAMD/NAMD_2.13_Linux-x86_64-multicore/namd2 +p24 +replicas 24
restart_${cnt}.conf --source FEP_remd_softcore.namd +stdout
output_${system}/%d/job${cnt}.%d.log

Please can anyone assist with information on how to get around this? Thanks
a lot.

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