Karan Kapoor
Postdoctoral Research Associate
Address:
Beckman Institute, Room 3115
University of Illinois at Urbana-Champaign
405 N. Mathews Ave.
Urbana, IL 61801
Telephone:
(217) 244-5883
E-mail:
Education
- Ph.D., Molecular Biophysics, 2015
University of Tennessee - Oak Ridge National Lab
- B.E., Biotechnology, 2009
Manipal Institute of Technology, India
Research Interests
Publications
(*Equal Contribution **Corresponding Author)
- Karan Kapoor, Sundar Thangapandian and Emad Tajkhorshid (2021)
Extended-ensemble docking to probe evolution of ligand binding sites in proteins undergoing large-scale structural changes for their function.
BioRxiv.
- Karan Kapoor*, Shashank Pant* and Emad Tajkhorshid (2021)
Active Participation of Membrane Lipids in Inhibition of Multidrug Transporter P-Glycoprotein.
Chemical Science, 12, 6293-6306.
- Defne Gorgun, Muyun Lihan, Karan Kapoor, and Emad Tajkhorshid (2021)
Binding Mode of SARS-CoV2 Fusion Peptide to Human Cellular Membrane.
Biophysical Journal, 20, 2914-2926.
- Sepehr Dehghani-Ghahnaviyeh, Karan Kapoor**, and Emad Tajkhorshid** (2021)
Conformational changes of the nucleotide binding domains of P-glycoprotein induced by ATP hydrolysis.
FEBS Letters, 595(6), 735-749.
- Karan Kapoor, Min Pi, Leigh Darryl Quarles, Satoru Kenneth Nishimoto, Jerome Baudry and Jeremy C Smith (2021)
Carboxylation Status of Osteocalcin has Important Consequences on its Structure and Dynamics.
Biochimica et Biophysica Acta- General Subjects, 1865(3): 129809.
- Sundar Thangapandian*, Karan Kapoor*, and Emad Tajkhorshid (2020)
Probing Cholesterol Binding and Translocation in P-glycoprotein.
Biochimica et Biophysica Acta - Biomembranes, 1862(1): 183090.
- Tao Jiang, Po-Chao Wen, Noah Trebesch, Zhiyu Zhao, Shashank Pant, Karan Kapoor, Mrinal Shekhar, Emad Tajkhorshid (2020)
Computational Dissection of Membrane Transport at a Microscopic Level.
Trends in Biochemical Sciences, 45(3): 202-216.
- Po-Chao Wen, Paween Mahinthichaichan, Noah Trebesch, Tao Jiang, Zhiyu Zhao, Eric Shinn, Yuhang Wang, Mrinal Shekhar, Karan Kapoor, Chun Chan, Emad Tajkhorshid (2018)
Microscopic View of Lipids and Their Diverse Biological Functions. Current Opinion in Structural Biology.
Current Opinion in Structural Biology, 51: 177-186.
- Min Pi*, Karan Kapoor*, Ruisong Ye, Dong-Jin Hwang, Duane D. Miller, Jeremy C. Smith, Jerome Baudry, L. Darryl Quarles (2018)
Computationally identified novel agonists for GPRC6A.
PLoS ONE, 13(4).
- Min Pi*, Karan Kapoor*, Ruisong Ye, Jeremy C. Smith, Jerome Baudry, Leigh D. Quarles (2018)
GPCR6A Is a Molecular Target for the Natural Products Gallate and EGCG in Green Tea.
Molecular Nutrition & Food Research, 62(8).
- Karan Kapoor, Derek J. Cashman, Barry D. Bruce, Jerome Baudry (2017)
Binding Mechanisms of Electron Transport Proteins with Cyanobacterial Photosystem I: An Integrated Computational and Experimental Model.
Journal of Physical Chemistry B, 122(3): 1026-1036.
- Karan Kapoor, Michael R. Duff, Amit Upadhyay, Joel C. Bucci, Arnold M. Saxton, Robert J. Hinde, Elizabeth E. Howell, Jerome Baudry (2016)
Highly Dynamic Anion-π Networks in Proteins.
Biochemistry, 55(43): 6056-6069.
- Wilfredo Evangelista, Rebecca L. Weir, Sally R. Ellingson, Jason B. Harris, Karan Kapoor, Jeremy C. Smith, and Jerome Baudry (2016)
Ensemble-Based Docking: From Hit Discovery to Metabolism and Toxicity Predictions.
Bioorganic & Medicinal Chemistry, 24(20): 4928-4935.
- Min Pi, Karan Kapoor, Ruisong Ye, Satoru K. Nishimoto, Jeremy C. Smith, Jerome Baudry, L. Darryl Quarles (2016)
Evidence for Osteocalcin Binding and Activation of GPRC6A in β-Cells.
Endocrinology, 157(5): 1866-1880.
- Karan Kapoor, Nicole McGill, Cynthia Peterson, Hal Meyers, Michael Blackburn, Jerome Baudry (2016)
Discovery of Novel Nonactive Site Inhibitors of the Prothrombinase Enzyme Complex.
Journal of Chemical Information and Modeling, 56(3): 535-547.
- Min Pi*, Karan Kapoor*, Yunpeng Wu, Ruisong Ye, Susan E. Senogles, Satoru K. Nishimoto, Dong-Jin Hwang, Duane D. Miller, Ramesh Narayanan, Jeremy C. Smith, Jerome Baudry and L. Darryl Quarles (2015)
Structural and Functional Evidence for Testosterone Activation of GPRC6A.
Molecular Endocrinology, 29(12): 1759-1773.
In News
Journal Covers
Front Cover
Biochimica et Biophysica Acta - Biomembranes, January 2020.
Back Cover
Chemical Science, May 2021.