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Summary of Results

How does this analysis indicate which molecules are more closely related to each other? In Exercise 1, we evaluated structure conservation on a moderate to high level and noticed when we changed highlighting style that the structural conservation is highest in the core. Sequence conservation, in Exercise 2, was also highest in the core of the molecule and at the dimerization site. We then further analyzed structure conservation during Exercise 3. We noticed that upon increasing the value of structure conservation, the highest structural conservation is among the three AspRSs. When the Q$\ge $0.7, no residues is SerRS had Q$\ge $0.7 with the three AspRS, indicating poor structure conservation. The three AspRS molecules are more closely related to each other in comparison to SerRS.
 
Having examined the relationship between the four AARSs using structure and sequence conservation, we will now use phylogenetic trees to display the evolutionary relationships graphically.



Brijeet Dhaliwal 2004-09-15