From: Mani Kandan (manikandand5110_at_gmail.com)
Date: Fri Oct 05 2018 - 21:49:03 CDT
Thanks! It helps a lot.
On Sat, Oct 6, 2018 at 1:28 AM Bassam Haddad <bhaddad_at_pdx.edu> wrote:
> Hi Mani,
> I wrote this python script that tells you what value you should put in the
> efield column (my code assumes you are placing the vector along the z-axis,
> which would be normal to a typical membrane simulation). Furthermore it
> will approximate the amount of time it would take to simulate the
> permeation of n ions, and conversely how many ion permeation events you can
> expect to see t time. These back of the envelope conversions come from a
> 2004 review by Benoit Roux (Roux, B., Allen, T., Bernèche, S., & Im, W.
> (2004). Theoretical and computational models of biological ion channels. *Quarterly
> Reviews of Biophysics,* *37*(1), 15-103. doi:10.1017/S0033583504003968)
> see equations 103, and 104 from the review. These calculations require a
> maximum conductance (gmax) that is known *a priori* from experiment, if
> this value isn't known just enter an arbitrary number and continue.
> I based this script off of the 'Electrostatic Maps and Ion
> Conduction' tutorial (
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