question about point substitution A→U

From: parinaz bashirbanaem (
Date: Sat Dec 30 2017 - 12:47:43 CST

Hi everyone,

I'm working with DNA-RNA complex and trying to convert an adenine group
into an uracil in RNA strand. In addition to, I want to retain hydrogen
bonding (Watson-crick) between aforementioned uracil and thymine (in DNA
strand) after conversion. Could anyone lead me towards how to perform this

Thank you very much for any suggestion.

Best regards,

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