Christopher Maffeo is a post doctoral researcher working with Aleksei Aksimentiev to develop and apply atomistic and coarse-grained simulation techniques to study biomolecular and biotechnological systems. His work has focused on DNA-DNA and DNA-protein interactions, highlighting the importance of the physical properties of DNA in determining its behavior. Christopher recently developed a coarse-grained model of single-stranded DNA interacting with single-stranded DNA binding protein that was capable of quantitatively matching experiment. Now he is actively working to develop features in the Center's software, ARBD, that allow such models to be simulated at scale with high efficiency using GPU accelerators.
Christopher Maffeo


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