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Hybrid MD-Go model

NAMD incorporates a hybrid MD-Go model (hereby referred to as Go) to study the conformation changes in biomolecular systems. The method replaces the physical-based nonbonded interactions with a smoother knowledge-based potential energy surface. Bonded interactions are taken from the classical force fields. By removing energetic traps along a MD trajectory, the system will be able to sample states not normally accessible to classical MD simulations.