Yunsen 'Vincent' Zhang
Vincent has a huge interest to explore nature of biophysics by developing computational methods including application and algorithm of molecular modeling and machine learning.
Home Department: Center for Biophysics and Quantitative Biology
Office Address: 3157 Beckman Institute, 405 N Matthews Ave, Urbana, IL 61801
Email Address: yunsenz2@illinois.edu
Education
University of Illinois Urbana-Champaign
- PhD student, Computational biophysics (from 15/08/2024 to now)
- Supervised by Dr. Emad Tajkhorshid
University of Macau
- Mphil, Computational pharmaceutics (from 08/08/2021 to 31/07/2023)
- Supervised by Dr. Defang Ouyang
Chengdu University of Traditional Chinese Medicine
- BSc, Pharmaceutics (from 06/09/2017 to 18/06/2021)
Research Interests
Application of molecular modeling in biophysical systems
- Exploration of lipid-mediated drug release mechanism of ABC transporter
- Prediction of drug permeability for cell membrane process with enhanced sampling algorithm
- Prediction of cohesive energy density of organic small molecules with molecular dynamics simulation
- Investigation of mRNA lipid nanoparticle via coarse-grained molecular dynamics simulation
- Molecular modeling for drug delivery systems including cyclodextrin, micelle, liposome, self-assembly nanoparticle, solid dispersion and etc
Software development
- FormulationMM
- Ion Channel Simulator (to be released)
- VMD-mcp (to be released)
- MsciPy (to be released)
- FormulationLNP (to be released)
Machine learning
- Integrating machine learning and molecular modeling to predict physical-chemical properties of biological systems
- AI-driven nanopore protein design
Publications
(Citations: 1014, h-index: 12, updated by 07/02/2025)Gallery
