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The physical Contents
How does this analysis indicate which molecules are more closely
related to each other? In Exercise 1, we evaluated structure
conservation on a moderate to high level and noticed when we changed
highlighting style that the structural conservation is highest in the
core. Sequence conservation, in Exercise 2, was also highest in the
core of the molecule and at the dimerization site. We then further
analyzed structure conservation during Exercise 3. We noticed that upon
increasing the value of structure conservation, the highest structural
conservation is among the three AspRSs. When the Q
0.7,
no residues is SerRS had Q
0.7 with the three
AspRS, indicating poor structure conservation. The three AspRS
molecules
are more closely related to each other in comparison to SerRS.
Having examined the relationship between the four AARSs using structure
and sequence conservation, we will now use phylogenetic trees to
display the evolutionary relationships graphically.
Brijeet Dhaliwal
2004-09-15