RE: equilibrate the bulk water system

From: Norman Geist (norman.geist_at_uni-greifswald.de)
Date: Wed Mar 11 2015 - 02:03:46 CDT

>From the Error message one can conclude instability of your system. The error message points out, that the grid charges for PME have changed more than expected between timesteps, which results from really fast atoms. The most likely reason are bad contacts in the initial structure and too short minimization. So increase the number of minimization steps to approx. 10000 steps. Also check the TOTAL energy of the system for convergence during the minimization run (VMDs Namd Plot plugin is useful for that).

 

For the latter NPT run, you are interested in:

 

useflexiblecell yes

useconstantarea yes

 

along with the piston pressure to have only Z changing.

 

Norman Geist.

 

From: owner-namd-l_at_ks.uiuc.edu [mailto:owner-namd-l_at_ks.uiuc.edu] On Behalf Of Hasan haska
Sent: Tuesday, March 10, 2015 10:52 PM
To: NAMD List
Subject: namd-l: equilibrate the bulk water system

 

Dear NAMD users,

 

I want to minimize and equilibrate a bulk water system that includes 7048 water molecules (SPC/E water model) in a rectangular box with the d=0.996 g/cm3 experimental density at 300K. Therefore I prepared a namd conf file below and started to run it. But after minimization was completed I got the error, which is in below. My aim is to run minimization and NPT simulation with keeping the dimension of the unit cell in the x-y plane constant while allowing fluctuations along the z axis in order to get the real cell sizes ( 55 X 55 X 70 Angs ) according to the density. Then run a NVT simulation with these cell size. How can I solve this problem ? Could you please share your opinion and experience ?

 

 

Thanks.

 

 

http://www.filedropper.com/water_1

 

My simulation files are in the link above.

 

 

*****************************

Error:

------------- Processor 0 Exiting: Called CmiAbort ------------

Reason: FATAL ERROR: Stray PME grid charges detected!

 

FATAL ERROR: See http://www.ks.uiuc.edu/Research/namd/bugreport.html

 

Charm++ fatal error:

FATAL ERROR: Stray PME grid charges detected!

 

**************************

 

 

 

#--- This is a test namd configuration file

#############################################################

##

#############################################################

 

paratypeCharmm on

parameters water.PRM

 

structure water.psf #

coordinates water_.pdb #

outputName water_1out #

 

set temperature 300

   

temperature $temperature

                   

firsttimestep 0

 

 

# Integrator Parameters

timestep 1.0

nonbondedFreq 2

fullElectFrequency 4

stepspercycle 16

 

 

# Force-Field Parameters

exclude scaled1-4

1-4scaling 1.0

cutoff 18.

switching on

switchdist 15.

pairlistdist 20.

 

 

# Constant Temperature Control

langevin on ;# do langevin dynamics

langevinDamping 1 ;# damping coefficient (gamma) of 5/ps

langevinTemp $temperature

langevinHydrogen on ;# couple langevin bath to hydrogens

 

 

# Constant Pressure Control (variable volume)

 

useGroupPressure no ;# needed for 2fs steps

useFlexibleCell yes ;# no for water box, yes for membrane

useConstantArea yes ;# no for water box, yes for membrane

 

langevinPiston on

langevinPistonTarget 1.01325 ;# in bar -> 1 atm

langevinPistonPeriod 200.

langevinPistonDecay 50.

langevinPistonTemp $temperature

 

 

#--- PBC

 

cellBasisVector1 55.0 0.0 0.0

cellBasisVector2 0.0 55.0 0.0

cellBasisVector3 0.0 0.0 100.0

 

 

#--- PME

PME yes

PMEGridSpacing 1.0

 

 

#--- Output & Restart

 

binaryoutput no

 

binaryrestart yes

 

restartname water_1restart #

DCDfile water_1out.dcd #

  

restartfreq 5000 #

dcdfreq 5000

xstFreq 5000

outputEnergies 5000

outputPressure 5000

outputtiming 5000

 

minimize 10000

reinitvels $temperature

run 10000000

# 10 ns 2002 record

 

 

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